Distribution of Hemoglobin Genotypes Amongst Residents in Port Harcourt
Abstract
A study of the distribution of haemoglobin genoctpes was carried out amongst the Igbos, Yorubas, and Hausas living in Port Harcourt, The study considered 156 adult subjects: 123 males, and 33 females. Electrophoresis was performed using standard methods. The results d s) showed that the mean and standard deviations (:7 of the haemoglobin (Hb) variants were HbAA (37.00=1.732), HbAS (14.67=2.309), and HbAC (0.33=0.058). The distribution of haemoglobin (Hb) among the subjects were HI,A..4 111 (71.15%), HbAS44(28.21%) and HbAC 1 (0.649-6). Among the males, 93(75.6196) were HbAA, 30(24.39%) were HbAS and no males had HbAC. Among the 44 females 18 (54.55%) were H5A-4, 14(42.42%) HbAS; and 1(3.0396) HbAC. The Percentage of patterns with Igbos were (HbAA 36(69.23%) and (HbAS 16(30.7796)), and Hausa were (Hb.A.A 39 (76.47%) and HbAS 12 (23.5396) and Yorubas were aHbA..4 36(67.9496), HbAS 16(30.1996) and HbAC 1 (1.89%)). In this work, the only HbAC encountered was observed among samples from the females. A high prevalence of variants _ACA and AS heamoglobin was observed in the population.
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